Down-regulation of hTERT Sensitizes Chemotherapeutic Effects of Docetaxel in Human Prostate Cancer Cells

Docetaxel is a chemotherapy treatment that is a last line of defense treatment for prostate cancer patients, but its effectiveness varies. Experimentation was conducted to determine if suppression of the immortalizing enzyme, telomerase in cancer cells, would enhance docetaxel treatment. Analysis of results suggests that suppressing telomerase before treatment with docetaxel produces a synergistic combination treatment.

Name: Ashoka Sanjaya Rajendra
Stats: 17 year-old Senior from Loudoun County Academy of Science in Sterling, VA
Influential Person: My Father
Career Goal: Continue to pursue research projects applicable to medicine, and in the long term become a doctor.
Field Interest: My father is an oncologist so I have been exposed to the clinical aspects of cancer from an early age. There is much room for improvement in cancer treatments that even a high school student can be a part of.

Tags: Add new tag, education, innovation, inspire, Intel, Intel International Science and Engineering Fair, Intel ISEF

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